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202010月份
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最後更新2020/10/23
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::: * 首頁 > 師資陣容new5 > 邱秀貞副教授

* * 邱秀貞副教授
*

友善列印

邱秀貞 副教授


一、學歷:

Ph.D. Chemistry & Biochemistry department, University of Delaware

二、經歷:

Aug. 2010-Now Associate Professor, National Chiayi University

Aug. 2005-July. 2010 Assistant Professor, National Chiayi University .

Aug. 2004-July. 2005 Post Doctor: Professor Liaw's lab, National Tsing Hua University , Shinchu , Taiwan .

Jun. 1994-Jun. 1996 Research Assistant: Professor Liaw's lab, National Changhua University of Education, Changhua ,  Taiwan .

三、專業領域:

Bioinorganic/organicmetallic Chemistry (生物無機/有機金屬化學 )

Metal biomedical materials (金屬生物醫學材料)

NO Release Agent for Repellent / Attraction of Mosquito (一氧化氮蚊蟲忌避/誘引材料之開發)

四、連絡方式( Tel or e-mail):

   05-271-7951

  genechiou@mail.ncyu.edu.tw

五、研究方向:

1. Biomimetic synthesis 

2. Self-assembly NO donor-RREs.

3. Water Spliting

4. Organometallic anti-cancer precursor complexes


六、期刊論文-校務系統研究成果

1. Yun-Chieh Sung1,2, Pei-Ru Jin1, Li-An Chu3, Fu-Fei Hsu4, Mei-Ren Wang5, Chih-Chun Chang1, Show-Jen Chiou6, Jiantai Timothy Qiu7,8,9, Dong-Yu Gao1, Chu-Chi Lin9, Yu-Sing Chen9, Yi-Chiung Hsu10, Jane Wang2, Fu-Nien Wang11, Pei-Lun Yu11, Ann-Shyn Chiang 3,12,13,14, Anthony Yan-Tang Wu15,16,17, John Jun-Sheng Ko1,15, Charles Pin-Kuang Lai 15,16,18, Tsai-Te Lu 1,5* Yunching Chen 1*, Delivery of nitric oxide with a nanocarrier

promotes tumour vessel normalization and potentiates anti-cancer therapies. Nature Nanotechnology, 2019, 12, 1160-1169.

 

2. Tsai-Te Lu*,, Yun-Ming Wang*,, Chen-Hsiung Hung*,§, Show-Jen Chiou*, Wen-Feng Liaw*, Bioinorganic Chemistry of the Natural Fe(NO)2 Motif: Evolution of a Functional Model for NO-Related Biomedical Application and Revolutionary Development of a Translational Model. Inorg Chem, 2018, 57, 12425-12443.

 

3. Tsai-Te Lu, Hsiao-Wen Huang, Chia-Her Lin, Yu-Ting Tseng, Wen-Feng Liaw, Hsi-Ya Huang, Show-Jen Chiou “DINITROSYL IRON COMPLEX, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, COMPOSITE MATERIAL COMPRISING THE SAME, AND USES THEREOF” Taiwan Patent No. 15/413,428, January 24, 2017.

 

4. Show-Jen Chiou; Yu-Der Wen, " Effects of curcumin on nitrosyl-iron complex-mediated DNA cleavage and cytotoxicity. Rong-Jen Shiau, Jheng-Yu Wu,," Planta Med, 2012, 78, 1342-1350.

 

5. Show-Jen Chiou 1, Arnold L. Rheingold 2, Glenn P.A. Yap, Charles G. Riordan,  Coordination chemistry of pyrazolylbis((alkylthio)methyl)borates: Hybrid nitrogen and sulfur donor ligands,  Inorganica Chimica Acta., 2010, 364, 81-88.

 

6. Chien-Hong Chen*, Show-Jen Chiou,*,and Hsuan-Yin Chen, Dinuclear [{Fe(NO)2}10-{Fe(NO)2}10] Dinitrosyl Iron Complex with Thiolate-CO-Bridged Ligands, Inorg. Chem., 2010, 49, 2023-2025.

 

7. Yu-Der Wen, Yun-Lung Ho, Rong-Jen Shiau, Jung-Kai Yeh, Jheng-Yu Wu, Wei-Lung Wang, Show-Jen Chiou*, Synergistic antitumor effect of curcumin and dinitrosyl iron complexes for against melanoma cells, J. Organomet Chem., 2010, 695, 352.

 

8. H.-H. Chang; H.-J. Huang; Y.-L. Ho; Y.-D. Wen; W.-N. Huang; S.-J. Chiou*.The water-soluble Roussin’s red ester acting as a potential photochemical NO-delivery agent: Photolysis reactions, DNA cleavage and anticancer activity. Dalton Trans, 2009, 6396.

 

9. S.-J Chiou*; C.-C. Wang, C.-M. Chang, Synthesis of dinitrosyl iron complexes (DNICs) with intramolecular hydrogen bonding. JOMC, 2008, 693, 3582.

 

七、研討會論文

1. Development of a novel plant extract for mosquito repellent and attractant. ICOM (19), 2018/11/24-2018/11/26, Taichung Taiwan.

 

2.  Dinitrosyl Iron Complexes with Bischromophoric Pyrene for Water Splitting, CSLT, 2017/12/01-2017/12/02, Chiayi Tauwan.

 

3. 新穎斑蚊忌避與誘引劑複合植物萃液液之開發, CSLT, 2017/12/01-2017/12/02, Chiayi Taiwan.

 

4. Roussin’s Red Esters as Luminescent Sensors and Carriers of Nitric Oxide, TBIC, 2016/11/15, Kaohsiung Taiwan.

 

5. Synthesis of Photochemical NO–Release Molecules (NO-RMs) with Biomolecular Vectors and their Anticancer Activity. ICBIC(16) 2013/7/22-2013/7/26 Grenbole France

 

6. Synthesis of Potential Photochemical NO–Release Molecules (NO-RM), DNICs & RREs with Specific Biomolecular Vectors. ASBIC(6) 2012/11/5-2012/11/8 Hongkong China  

 

八、研究計畫

1. 2017/06/01-2018/10/31產學合作計畫-新穎蚊子忌避與誘引劑材料之開發、測試與應用。(科技部)

 

2. 2015/09/01-2016/05/31創新環保綠色商機:複合型天然美白化妝品開發整合服務計畫。(SBIR)

 

3. 2014/08/01-2015/07/31水相光敏含螢光基團具一氧化氮釋放能力之金屬錯合物:合成,特質, DNA斷切及抗癌能力之探討。(科技部)

 

4. 2014/06/20-2014/10/20化妝保養品中天然抗UV原料的創新與開發。(經濟部)

 

5. 2011/08/01-2014/07/31  水溶性、光敏含鐵一氧化氮化合物之設計合成、性質、 DNA切割及抗癌活性之探討。(國科會)

 

6. 2010/08/1-2011/7/31  由結合氨基酸及胜 之水溶性 2-雙羥甲基磷 -1-硫醇乙烷所修飾之亞硝化鐵錯合物 :合成、特性、 DNA斷切及抗腫瘤效應之探討。( 國科會)

 

7. 2009/08/01-2010/07/31 潛力之光化學一氧化氮藥物前驅物之合成、光反應、DNA切割及蛋白質活化。( 國科會)

 

8. 2008/08/01-2009/07/31生化擬態之DNICRRE性質探討:結構及一氧化氮釋放對DNA切割及蛋白質。( 國科會)

 

9. 2007/08/01-2008/07/31生化擬態之DNICRRE性質探討:結構及一氧化氮釋放對DNA切割及蛋白質活化的影響。( 國科會)

 

10. 2005/08/01—2007/07/31 Synthetic Modeling of Protein-Bound Dinitrosyl Iron Complexes (DNICs)/Roussin's Red Ester (RREs) and the

Effect of Hydrogen Bonding( 國科會)

 

十、教授課目

無機化學、觸媒化學、高等無機化學、有機金屬化學、生物無機化學、環境化學特論、通識-科學與生活




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