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最後更新2019/11/01
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::: * 首頁 > 師資陣容 > 專任教師 > 吳青芬助理教授

* * 吳青芬助理教授
*

友善列印

教師姓名:吳青芬 Ching Fen Wu

    職:助理教授

    歷:德國美茵茲大學(Johannes Gutenberg-Universität Mainz)藥學暨生物化學研究所博士
        國立陽明大學 傳統醫藥研究所碩士
       國立中興大學 獸醫系獸醫學學士

E-mail cfwu@mail.ncyu.edu.tw
   話:05-2732960

簡要經歷:國立嘉義大學獸醫系  助理教授
                    財團法人農業科技研究院動物科技研究所  研究員
                    財團法人國家衛生研究院  博士後研究員

                    高雄醫學大學醫學院  博士後研究員
                    行政院國家科學委員會與德國學術交流總署(NSC/DAAD)博士班研究生赴德研究訪問三明治計畫

                    專門技術人員高等考試-公職獸醫師考試及格

研究興趣:天然物分子藥理、肝臟疾病之分子機制探討、保健食品研發

主要教授課程:獸醫臨床病理學及實習、獸醫藥理學、獸醫毒理學

研究著作:

期刊論文:

1. Fang CC*, Wu CF*, Liao YJ, Huang SF, Chen M, Chen YM. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage. Sci. Rep., 2018, 8(1):13802. (*:equal contribution)

2. Hong C, Cao J, Wu CF, Kadioglu O, Schüffler A, Kauhl U, Opatz T, Thines E, Efferth T. The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through Keap1-Nrf2/HO-1 pathway. Sci. Rep. 2017, 7(1):11551.

3. Hong C, Schüffler A, Kauhl U, Cao J, Wu CF, Opatz T, Thines E, Efferth T. Identification of NF-κB as determinant of posttraumatic stress disorder and its inhibition by the Chinese herbal remedy Free and Easy Wanderer. Front. Pharmacol.2017, 8:181.

4. Seo EJ, Wu CF, Ali Z, Wang YH, Khan SI, Walker LA, Khan IA, Efferth T. Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells. Front. Pharmacol.. 2016, 7:398.

5. Efferth T, Banerjee M, Paul N, Abdelfatah S, Arend J, Elhassan G, Hamdoun S, Hamm R, Hong C, Kadioglu O, Naß J, Ochwangi D, Ooko E, Ozenver N, Saeed M, Schneider M, Seo EJ, Wu CF, Yan G, Zeino M, Zhao Q, Abu-Darwish M, Andersch K, Alexie G, Bessarab D, Bhakta-Guha D, Bolzani V, Dapat E, Donenko F, Efferth M, Greten H, Gunatilaka L, Hussein A, Karadeniz A, Khalid H, Kuete V, Lee IS, Liu L, Midiwo J, Mora R, Nakagawa H, Ngassapa O, Noysang C, Omosa L, Roland FH, Shahat A, Saab A, Saeed E, Shan L, Titinchi S. Biopiracy of natural products and good bioprospecting practice. Phytomedicine. 2016, 23(2): 166-173.

6. Wu CF, Seo EJ, Klauck SM, Efferth T. Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic cells. Phytomedicine 2016, 23(2): 174-180.

7. Wu CF, Bohnert S, Thines E, Efferth T. Cytotoxicity of the root extract of Salvia miltiorrhiza against multidrug-resistance cancer cells. Am. J. Chin. Med. 2016, 44(4): 871-894.

8. Wu CF, Karioti A, Rohr D, Bilia AR, Efferth T. Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells. Food Chem. 2016, 201: 292-297.

9. Wu CF, Klauck SM, Efferth T.Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells.Arch. Toxicol. 2016, 90(9): 2275-2286.

10. Wu CF, Hong C, Klauck SM, Efferth T. Molecular mechanisms of rosmarinic acid in acute lymphoblastic leukemia cells. J. Ethanolpharmacol. 2015, 176:55-68.

11. Wu CF, Efferth T. Miltirone induces G2/M cell cycle arrest and apoptosis in CCRF-CEM acute lymphoblastic leukemia cells. J. Nat. Prod. 2015, 78(6):1339-1347.

12. Dörsam B,Wu CF,, Efferth T, Kaina B, Fahrer J. The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage.Arch. Toxicol2015, 89(5):797-805.

13. Hamm R, Chen YR, Seo EJ, Zeino M,Wu CF, Müller R, Yang NS,Efferth T. Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells.Biochem. Pharmacol. 2014, 91(1):18-30.

14. Wu CFLin YL, Huang YT. Hepatitis C virus core protein stimulates fibrogenesis in hepatic stellate cells involving the obese receptor.J. Cell. Biochem.2013, 114(3):541-550

15. Lin YL, Wu CF, Huang, YT. Effects of Rhubarb on migration of rat hepatic stellate cells.J. Gastroenterol. Hepatol.2009, 24(3):453-61

16. Lin YL, Wu CFHuang, YT. Phenols from the roots of Rheum palmatumattenuates chemotaxis in rat hepatic stellate cells.Planta Med. 2008, 74(10):1246-52.

17. Hsu YC, Chiu YT, Cheng CC, Wu CF, Lin YL, Huang, YT. 2005. Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis. J. Gastroenterol. Hepatol, 2007, 22(1): 99-111.

18. Hsu YC, Chiu YT, Lee CY, Wu CF, Huang, YT. Antifibrotic effects of tetrandrine on bile duct ligated rats. Can. J. Physiol. Pharmacol. 2006, 84(10): 967-976.

 

專書著作:

1. Wu CF, Efferth T. (2017) Anticancer activity of Salvia miltiorrhiza secondary metabolites, in Salvia Biotechnology (eds V. Georgiev and A. Pavlov), Springer International Publishing. pp. 179-208. Doi: 10.1007/978-3-319-73900-7_5

2. Seo EJ, Wu CF, Greten HJ, Efferth T. (2015) Epidermal growth factor receptors and downstream signalling pathways as cancer treatment targets for medicinal plants, in Ethnopharmacology (eds M. Heinrich and A. K. Jäger), John Wiley & Sons, Ltd, Chichester, UK. pp.169-178. Doi:10.1002/9781118930717.ch16



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