回首頁
* 應用化學系暨研究所 *
::: * 回首頁 *|* 嘉義大學 *|* 網站導覽 *|* 常見問答 *|* 意見信箱 *|* 雙語詞彙 *|* English *
*
**
*
*
:::
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
* 學生專區
*
*
*
*
*
*
*
*
*
*
*
*
*
*
* 入學資訊
*
*
*
*
*
*
*
*
* 畢業系友專區
*
*
*
*
*
*
*
*
*
*
* 活動資訊
*
*
*
*
*
*
*
*
*
*
*
*
* 服務項目
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
* 相關連結
*
*
*
*
*
*


20215月份
            [1]
[2] [3] [4] [5] [6] [7] [8]
[9] [10] [11] [12] [13] [14] [15]
[16] [17] [18] [19] [20] [21] [22]
[23] [24] [25] [26] [27] [28] [29]
[30] [31]          

最後更新2021/05/14
*
::: * 首頁 > 師資陣容new5 > 陳清玉副教授

* * 陳清玉副教授
*

友善列印

陳清玉 副教授教授近照

一、學歷:

美國 Texas A&M University 化學博士

二、經歷:

1993 Texas A&M University 博士後研究員

1993-1994 台灣大學藥學系博士後研究員

1995-1996 成功大學化學系博士後研究員

1996-2003 朝陽科技大學應用化學系暨研究所副教授

2003-present 嘉義大學應用化學系暨研究所副教授

三、專業領域:

有機化學、自由基化學、天然藥物化學、 有機化合物純化與鑑定

四、連絡方式( Tel or e-mail):

  052717970

  cychern@mail.ncyu.edu.tw

五、研究方向:

 主要研究方向有二:

‧ 合成有潛力的血小板凝集拮抗劑

‧ 利用自由基方法開發新的合成方法及反應機構的研究

六、期刊著作:校務系統研究成果

1.      D. H. R. Barton, C. Y. Chern, J. Cs. Jaszberenyi, 1992, " Synthesis Of Substituted Malonic Acids from Carbon Radicals" , Tetrahedron Lett. , 33, 7299-7302.

2.      D. H. R. Barton, C. Y. Chern, J. Cs. Jaszberenyi, 1992, " Two Carbon Homologation Of Carboxylic Acids" , Tetrahedron Lett. , 33, 5017-5020.

3.      D. H. R. Barton, C. Y. Chern, J. Cs. Jaszberenyi, 1992, " Homologation Of Carboxylic Acids By Improved Method Based On Radical Chain Chemistry" , Tetrahedron Lett. , 33, 5013-5016.

4.      D. H. R. Barton, C. Y. Chern, J. Cs. Jaszberenyi, T. Shinada, 1993, " Chain-Elongation and Degradation of Carboxiic Acids by Barton-Ester Based Radical Chemistry" , Tetrahedron Lett. , 34, 6505-6508.

5.      D. H. R. Barton, C. Y. Chern, C. Tachdjian, 1994, "Ration Of New Thiohydroxamic Derivatives; Synthesis of Substituted l-Hydroxy-l,2-Dihydroimidazole-2-Thiones" , Heterocycles , 37, 793-805.

6.      D. H. R. Barton, C. Y. Chern, J. Cs. Jaszberenyi, 1995, " The Invention Of Radical Reactions. Part XXXIV. Homologation  Of Carboxylic Acids to a Keto Carboxylic Acids by Barton-Ester Based Radical Chain Chemistry" , Tetrahedron , 51, 1867-1886.

7.      D. H. R. Barton, C. Y. Chern, J. Cs. Jaszberenyi, 1995, " The Invention Of Radical Reactions. XXXIII Homologation Reactions Of Carboxylic Acids By Radical Chain Chemistry", Aust. J. Chem. , 48, 407-425.

8.      S. J. Wu, I. S. Chen, C. Y. Chern, C. M. Tseng, T. S. Wu, 1996, " Structure And Synthesis of Simulansamide, A Platelet Aggregation Form Zanthoxylum Simulans", J. Chin. Chem. Soc. , 43,195.

9.      T. S. Wu, Y. Y. Chan, Y. L. Leu, C. Y. Chern C. F. Chen, 1996, " Cytotoxic Principles From Nothapodytes Foetida(ll) Nothapodytine A and B Two New Alkaloids from Nothapodytes Foetida", Phytochemistry, 42, 907.

10.  T. S. Wu, L. S. Shi, S. C. Kuo, C. Y. Chern, S. F. Tung, C. M. Teng, 1997, "Platelet Aggregation Inhibitor from Gamoderma Lucidum", J Chin Chem. Soc. , 44, 157.

11.  T. S. Wu, Y. C. Wu, P. L. Wu, C. Y. Chern, Y. L. Leu, Y. Y. Chan, 1998, “ Structure and Synthesis of [n]-Dehydroshogaols from Zingiber officinale ” , Phytochemistry , 48 , 889.

12.  T. S. Wu, H. C. Hsu, P. L. Wu, Y. L. Leu, Y. Y. Chan, C. Y. Chern, M. Y. Yeh, H. J. Tein, 1998, “ Naphthoquinone Esters from the root, of Rhinacanthus nasutus ” , Chem. Pharm. Bull. , 46, 413.

13.  W. M. Kan, C. Y. Chem, S. F. Su, 1998, "Synthesis of l-(2-Carboxyethylbenzyl)- 2-benzenesulfonamidobicyclo[ 2.2.1 ]heptane: A Novel Potent Thromboxane Antagonist", J. Chin. Chem. Soc ., 45, 711.

14.  陳清玉 , 2000, “ 九二一震災後化學實驗室安全的省思 ” , Chemistry, 58, A10-A12.

15.  C. Y. Chern, Y. L. Yek, J. D. Jan, W. M. Kan, 2001, “ Synthesis of the chair Pair of a Novel Thromboxane Antagonist, 3-[2-(3-Benezenesulfonylamino-7-oxabicyclo [2,2,2]hept-2-yl-methyl)phenyl]propionic Acid ” , J. Chin. Chem. Soc ., 48, 907-912.

16.  C. Y. Chern, Y. P. Huang, W. M. Kan, 2003, “ Selective N -debenzylation of Amides with p -TsOH. ” , Tetrahedron Lett ., 44, 1039-1041.

17.  W. M. Kan, Y. L. Yek, Y. H. Wang, C. Y. Chern, 2003, “ Synthesis of 4-Aza-3-oxo- androstane-17 b -carboxylic Acid, a Key Intermediate for the Preparation of Potent 5 a -Reductase Inhibitors ” , Chin. Pharm. J. 55 , 213-219.

18.  W. M. Kan, C. L. Cheng, C. Y. Chern, 2004, “ One-Pot Synthesis of Ene-Lactams via N -Debenzylation of Keto- Containing N -2,4-Dimethoxyylbenzylamides ” , Synth. Commun. 34 , 4257-4264.

19.  C. Y. Chern , S. J. Chen, W. M. Kan, 2005, “ Design and Synthesis of 3-Aryl-5-Alicyclic-[1,2,4]-oxadiazoles as Novel Platelet Aggregation Inhibitors ” , J. Chin. Chem. Soc . 52 , 331-338.

20.  洪巧珍 , 陳家鐘 , 陳清玉 , 彭淑貞 , 莊益源 , 陳昇寬 , 王文哲 , 蔡恕仁 , 李木川 , 顏辰鳳 , 洪銘德 , 2005 “ 楊 桃花姬捲葉蛾性費洛蒙產品與應用 ”, Formosan Entomol. Spec. Pub. 7 , 29-58.

21.  W . M. Kan, S. H. Lin , C. Y. Chern, 2005, “ Efficient Synthesis of 2-( N -Substituted)-2-imidazolines and 2-( N -Substituted)-1,4,5,6-tetrahydropyrimidines ” , Synth. Commun. 35, 2633-2639.

22.  T. L. Hwang, S. H. Yeh, Y. L. Leu, C. Y. Chern, H. C. Hsu, 2006,“Inhibition of superoxide anion and elastase release in human neutrophils by 3’-isopropoxychalcone via a cAMP-dependent pathway”, Br. J. Pharmacol. 148, 78-87.

23.  H. W. Shen, Y. L. Chen, C. Y. Chern, W. M. Kan, 2007, “The effect of prostacyclin agonists on the differentiation of phorbol ester treated human erythroleukemia cells”, Prostaglandins and other Lipid Mediators (accepted).

24.  C. Y. Chern, Y. L. Yek, Y. L. Chen, W. M. Kan, 2008, “Synthesis of 2-[4-(Imidazolin-2-ylideneamino)benzyl]-indan-1-ones as Novel Potent Prostacyclin Antagonists”, J. Chin. Chem. Soc.

25.  S. L. Wang, J. M. Lin, S. E. Shu, C. Y. Chern, 2010, “Influences of protonation and hydrogen bonding on intramolecular charge transfer compounds possessing different spacers”, J. Photochem. Photobiol. A: Chem.

26.  H. Chen ,* W. H. Wang , Y. H. Wang , Z. Y. Lin , C. C. Wen, C. Y. Chern * , 2013, “Evaluation of the Anti-Inflammatory Effect of Chalcone and Chalcone Analogues in a Zebrafish Model”, Molecule 18, 2052-2060.

27.  Y. T. Lee, T. H. Fong ,H. M. Chen ,C. Y. Chang ,Y. H. Wang ,C. Y. Chern ,* and Y. H. Chen * , 2014, “Toxicity Assessments of Chalcone and Some Synthetic Chalcone Analogues in a Zebrafish Model”, Molecule 19, 641-650.

28.  H. C. Shih, C. Y. Chern, P. C. Kuo, Y. C. Wu, Y. Y. Chan, Y. R. Liao, C. M. Teng and T. S. Wu, 2014, “Synthesis of Analogues of Gingerol and Shogaol, the Active Pungent Principles from the Rhizomes of Zingiber officinale and Evaluation of Their Anti-Platelet Aggregation Effects”, International Journal of Molecular Sciences 15, 3926-3951.

29.  陳清玉, 2015, “Pro-Angiogenic Effects of Chalcone Derivatives in Zebrafish Embryos in Vivo”, Molecules 20, 12512-12524.

30. S.-E. Tsai, K.-H. Chiang, C.-C. Tseng, N.-W. Chen, C.-Y. Chern,*  and F.-F. Wong,* " Facile One-pot Synthesis of Methyl 1-Aryl-1H-1,2,4-triazole-3-carboxylates from Nitrilimines with Vilsmeier Reagent", Eur. J. Org. Chem. 2019, 1754-1762.

七、 研討會論文

  1. C. Y Chern, Y. S. Wang, W. M. Kan, “ The Synthesis of a Novel 5 α -Reductase Photoaffinity Label ” , 87 年化學年會 .
  2. J. D. Yan, E. P. Huang, C. Y. Chern, W. M. Kan, E. H. Chen, “ Design and Synthesis of Thromboxane An Tagonists ” , 88 年化學年會 .
  3. C. C. Wang, J. Y. Chuang, C. Y. Chern, “ The Synthesis of photoaffinity Label and the Methodology Study of the Heteroannulation ” , 89 年化學年會 .
  4. C. Y. Chern, W. M. Kan, Y. P. Huang, Y. C. Chiang, M. Z. Her, “ The Methodology study and Application of Intramolecular Heteroannulation by p-Toluenesulphonic acid ” , 90 年化學年會
  5. C. Y. Chern, Y. L. Hsueh, W. L. Lu, T. H. Huang, C. L. Chen, “ Determination of the steric chemistry of 15-hydroxy-prostanoids by Mosher ' s reagent ” , 92 年化學年會

八、研究計畫:

年 度

計 畫 名 稱
補助機關
89
利用 GRIGNARD 試劑進行不對稱合成
國科會
90
不對稱 grignard 反應的應用
國科會
9 0
昆蟲性費洛蒙 -8 , 12 烯醇乙酸酯的合成
農委會

9 1

楊桃花姬捲葉蛾性費洛蒙引誘劑主成份合成技術之開發( 產學合作第一年 )
國科會

92

利用對甲基苯磺酸選擇性將 N-2,4- 二甲 氧基甲基苯胺 進行去 N- 甲基苯化

國科會

92

楊桃花 姬 捲葉蛾性費洛蒙引誘劑主 成份合成技術之開發 ( 產學合作第二年 )

農委會

94

血栓素拮抗劑 2-substituted-5-morpholin-4-yl-indan-1-one衍生物的合成與開發

國科會

九、其他:

十、教授課目:

有機化學、有機光譜、高等有機化學、有機合成



*

到頁面頂端

*

回上一頁


國立嘉義大學 版權所有 Copyright © 2017 All Rights Reserved.

歡迎來電05-2717899,傳真05-2717901 或 e-Mail:appchem@mail.ncyu.edu.tw 賜教

         

         畢業壁報展                                 分析年會                                      系k           

 

 

 

*