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Wen-Chang, Chang, Ph. D.

Dr. Wen-Chang, Chang Associate professor

Professor with Department of Food Science

MajorFood Processing, and Food Safety, Development and Innovation on    Agricultural Waste Processing, Functional Foods, Carbohydrate Metabolism

Tel: 886-5-2717593

Fax: 886-5-2717596

E-mail: wcchang@mail.ncyu.edu.tw

Dr. Wen-Chang, Chang


(A) Published papers

  1. Chia-Feng Wu, Han Cheng,  Wen-Chang Chang, Ming-Chang Wu,  and Jen-Shinn Lin.Use of highly methoxyl-esterified cross-linked alcohol insoluble substance to remove pectinesterase for the reduction of methanol in sweet orange wine.  Journal of pure and applied microbiology  2017,  11(3), 1-11.
  2. Da-Wei Huang,  Wen-Chang Chang, James Swi-Bea Wu, Rui-Wen Shih, and Szu-Chuan Shen. Vescalagin from Pink wax apple [Syzygium samarangense (Blume) Merrill and Perry] alleviates hepatic insulin resistance and ameliorates glycemic metabolism abnormality in rats fed a high-fructose diet.  Journal of agricultural and food chemistry  2016,  64, 1122-1129.  (Co-first author).  (SCI).
  3. Wen-Chang Chang  , James Swi-Bea Wu, Chen-Wen Chen, Po-Ling Kuo, Hsu-Min Chien, Yuh-Tai Wang and Szu-Chuan Shen. Protective effect of vanillic acid against hyperinsulinemia, hyperglycemia and hyperlipidemia via alleviating hepatic insulin resistance and inflammation in high-fat diet (HFD)-fed rats.  Nutrients  2015,  7(12), 9946-9959.  (First author)  (SCI).
  4. Da-Wei Huang,  Wen-Chang Chang, James Swi-Bea Wu, Rui-Wen Shih, and Szu-Chuan Shen. Gallic acid ameliorates hyperglycemia and improves hepatic carbohydrate metabolism in rats fed a high-fructose diet.  Nutrition Research  2016, 36(2), 150-160.  (Co-first author)  (SCI).
  5. An-Sheng Cheng, Yu-Hsiang Cheng, Chi-Ying Lee, Chin-Yuan Chung, and  Wen-Chang Chang*. Resveratrol protects against methylglyoxal-induced hyperglycemia and pancreatic damage  in vivo.  Nutrients  2015, 7: 2850-2865.  (Corresponding author)(SCI).
  6. Wen-Chang Chang  , Po-Ling Kuo, Chen-Wen Chen, James Swi-Bea Wu, and Szu-Chuan Shen. Caffeic acid improves memory impairment and brain glucose metabolism via ameliorating cerebral insulin and leptin signaling pathways in high-fat diet induced hyperinsulinemic rats.  Food Research International  2015, 77(1), 24-33.  (First author)(SCI).
  7. Wen -Chang Chang  , Shinn-Chih Wu, Kun-Di Xu, Bo-Chieh Liao, Jia-Feng Wu and An-Sheng Cheng. Scopoletin protects against methylglyoxal-induced hyperglycemia and insulin resistance mediated by suppression of advanced glycation endproducts (AGEs) generation and anti-glycation.  Molecules  2015  , 20: 2786-2801.  (First author)  (SCI).
  8. Wen-Chang Chang  , Szu-Chuan Shen, and James Swi-Bea Wu. Protective effects of vescalagin from Pink wax apple [Syzygium samarangense  (Blume) Merrill and Perry] fruit against methylglyoxal-induced inflammation and carbohydrate metabolic disorder in rats.  Journal of agricultural and food chemistry  2013, 61 (29): 7102-7109.  (First author)  (SCI).
  9. Wen-Chang Chang  , and Szu-Chuan Shen. Effect of water extracts from edible Myrtaceae plants on uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) in tumour necrosis factor-α-treated FL83B mouse hepatocytes.  Phytotherapy Research  2013, 27: 236-243.  (First author)  (SCI).
  10. Szu-Chuan Shen,  Wen-Chang Chang,  and Chiao-Li Chang. An extract from wax apple (Syzygium samarangense  (Blume) Merrill and Perry) effects glycogenesis and glycolysis pathways in tumor necrosis factor-α-treated FL83B mouse hepatocytes.  Nutrients2013, 5: 455-467.  (Co-first author)  (SCI).
  11. Bao-Hong Lee, Chia-Chen Lee, Yu-Hsiang Cheng,  Wen-Chang Chang, Wei-Hsuan Hsu, and She-Ching Wu. Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia.  Food and Chemical Toxicology.  2013, 62: 492–498. (SCI).
  12. Szu-Chuan Shen and  Wen-Chang Chang. Hypotriglyceridemic and hypoglycemic effects of vescalagin from Pink wax apple [Syzygium samarangense (Blume) Merrill and Perry cv. Pink] in high-fructose diet-induced diabetic rats.  Food Chemistry  2013, 136: 858-863. (SCI).
  13. 2018/8,Ying-Che,Huang,Bo-Hua,Wu,,,Yung-Lin,Chu,,,Wen-Chang,Chang,and,Ming-Chang,Wu,Effects of Tempeh Fermentation with Lactobacillus plantarum and Rhizopus oligosporus on Streptozotocin-Induced Type II Diabetes Mellitus in Rats,nutrients,2018,10(9),1143.
  14. 2019/6, Wen-Chang Chang,Da-Wei Huang, Martin Lo, Qin-Qiao Tee, Po-Ling Kuo, James Swi-Bea Wu,Protective effect of caffeic acid against Alzheimer's disease pathogenesis viamodulating cerebral insulin signaling, β amyloid accumulation and synapticplasticity in hyperinsulinemic rats., Journal of agricultural and foodchemistry, 67 , 7684 − 7693.
  15. 2019/9, Yuwen Ting,Yin‐Ting Hu, Jing‐Yu Hu, Wen‐Chang Chang, Qingrong Huang, Shu‐Chen Hsieh,Nanoemulsified adlay bran oil reduces tyrosinase activity and melanin synthesisin B16F10 cells and zebrafish, Food Science and Nutrition, 7 , 3216-3223.
  16. 2019/9, Wen-Chang Chang,Yin-Ting Hua, Qingrong Huang, Shu-Chen Hsieh, Yuwen Ting, Development of ATopical Applied Functional Food Formulation: Adlay Bran Oil Nanoemulgel, LWT -Food Science and Technology, 117 , 108619.
  17. 2019/10,Chih-Yuan,Ko,Ru-Hai,Lin,Yangming,Martin,Lo,Wen-Chang,Chang,,Da-Wei,Huang,James,Swi-Bea,Wu,Yu-Fang,Chang,Wen-Chung,Huang,Szu-Chuan,Shen,Effect of Ruellia tuberosa L. on aorta endothelial damage-associated factors in high-fat diet and streptozotocin-induced type 2 diabetic rats,Food,science &,Nutrition,2019;7:3742–3750.
  18. 2020/9,Da-Wei,Huang,Yangming,Martin,Lo,Wen-Chang,Chang,Chia-Yu,Lin,Jou-An,Chen,James,Swi-Bea,Wu,Wen-Chung,Huang,Szu-Chuan,Shen,Alleviative effect,of,Ruellia,tuberosa,L.on NAFLD and hepatic lipid accumulation via modulating hepatic de novo lipogenesis in high-fat diet plus streptozotocin-induced diabetic rats,Food science & Nutrition,2020;8:5710–5716.
  19. 2021/7,Wen-Chang,Chang,James,Swi-Bea,Wu,and,Szu-Chuan,Shen,Vescalagin from Pink Wax Apple (Syzygium samarangense,(Blume) Merrill and Perry) Protects Pancreatic β-Cells against Methylglyoxal-Induced Inflammation in Rats,Plants,2021,10(7),1448.
  20. 2021/3,Chih-Yuan,Ko,Yangming,Martin,Lo,Jian-Hua,Xu,Wen-Chang,Chang,Da-Wei,Huang,James,Swi-Bea,Wu,,Cho-Hua,Yang,Wen-Chung,Huang,Szu-Chuan,Shen,Alpha-lipoic acid alleviates NAFLD and triglyceride accumulation in liver via modulating hepatic NLRP3 inflammasome   inflammasome activation,pathway in type 2 diabetic rats,Food science&Nutrition,2021;9:2733–2742.