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Yu-Ju Chen

Yu-Ju Chen  教授近照
Title: Adjunct Professor
Education: Ph.D., Iowa State University
Research Area: Biophysical Chemistry, NMR
Tel: 886-2-27898660

e-mail: yjchen@ccvax.sinica.edu.tw

Research Interests:
  • Electrospray Mass Spectrometry
  • Bio-Targeted Molecules
Publications:
  1. “Mechanistic Aspect of Co(HAPP)(TFA)2 in DNA Bulge-Specific Recognition” Chien-Chung Cheng*, Wei-Chun Huang-Fu, Kuo-Chan Hung, Po-Jui Chen, Wen Jwu Wang, and Yu-Ju Chen*, Nucleic Acid Res . 31 , 2227-2233 (2003).
  2. “Quantitative proteomic analysis of metabolic regulation by copper ions in methylococcus capsulatus (Bath)”,Wei-Chun Kao, Yat-Ren Chen, Eugene C. Yi, Hookeun Lee, Qiang Tian, Keh-Ming Wu, Shih-Feng Tsai, Steve S. -F. Yu, Yu-Ju Chen, Ruedi Aebersold, and Sunney I. Chan, J. Biol. Chem. , 279 , 51554-51560 (2004).
  3. “Identification of Acute Phase Proteins in Sera of Nude Mice Inoculated with Human Cancer Cells Using Proteomics Techniques” Hsueh-Fen Juan, Jenn-Han Chen*, Wei-Tse Hsu, Su-Ching Huang, Shui-Tein Chen, John Yi-Chung Lin, Yu-wang Chang, Chih-Yin Chiang, Li-Li Wen, De-Chuan Chan, Yao-Chi Liu, Yu-Ju Chen*, Proteomics , 4 , 2766-2775 (2004) (featured as cover story) .
  4. “Plasma proteome of Severe Acute Respiratory Syndrome (SARS) analyzed by two-dimensional gel electrophoresis and mass spectrometry”, Jenn-Han Chen*, Yu-Wang Chang, Chen-Wen Yao, Tzong-Shi Chiueh, Su-Chin Huang, Ko-Yi Chien, An Chen, Feng-Yee Chang, Chi-Huey Wong, and Yu-Ju Chen*, Proc. Natl. Acad. Sci. USA., 101 , 17039-17044 (2004).
  5. “Structural characterization of sialic acid synthase by electrospray mass spectrometry a tetrameric enzyme composed of dimeric dimers” Hsin-Hung Huang, Hsin-Kai Liao, Tzann-Shun Hwang, Yi-Han Lin, Chun-Hung Lin and Yu-Ju Chen*, J. Am. Soc. Mass Spectrom. 16, 324-332 (2005)
  6. “Carbohydrate-Encapsulated Gold Nanoparticle for Rapid Target Protein Identification and Binding Epitope Mapping” Yu-Ju Chen*, Shu-Hua Chen, Yuh-Yih Chien, Yu-Wan Chang, Hsin-Kai Liao, Chih-Yang Chang, Mi-Dan Jan, Ken-Tseng Wang, and Chun-Cheng Lin*, ChemBioChem, 6 ,1169-1173
  7. “Nanoprobe-Based Affinity Mass Spectrometry for Selected Protein Profiling in Human Plasma” Po-Hung Chou, Shu-Hua Chen, Hsin-Kai Liao, Po-Chiao Lin, Gour Rong Her, Alan Chuan-Ying Lai, Chun-Cheng Lin,* and Yu-Ju Chen,* Anal. Chem . 77 , 5990-5997 (2005)
  8. “Determination of SMN1/SMN2 Gene Dosage by a Quantitative Genotyping Platform Combining Capillary Electrophoresis and MALDI-TOF Mass Spectrometry.” Hung-Yi Kao, Yi-Ning Su, Hsin-Kai Liao, Ming S. Liu, and Yu-Ju Chen, Clin. Chem. 52 , 361-369 (2006)
  9. “Ethylene Glycol-Protected Magnetic Nanoparticles for Multiplexed Immunoassay in Human Plasma.” Po-Chiao Lin, Po-Hung Chou, Shu-Hua Chen, Hsin Kai Liao, Kai-Yi Wang, Yu-Ju Chen,* and Chun-Cheng Lin,* Small , 2 , 485-489 (2006)