National Chiayi University

Shang-Ting Tsai   

Title：

Education： Ph.D., National Taiwan University

Experiences :

Research Area：

Glycomics, Analytical Chemistry, Physical Chemistry, Instrument Improvement, Design and Manufacturing

Tel:

e-mail:sttsai@mail.ncyu.edu.tw

Research Interests：

Method and Instrument Development of Glycan Identification Using Mass Spectrometry;

Investigation of Glycan Dissociation Mechanisms;

Method and Instrument Development of Extraction and Separation of Organic Molecules.

Publications：

Paper

1.        Wei-Chien Weng, Hung-En Liao, Shih-Pei Huang, Shang-Ting Tsai, Hsu-Chen Hsu, Chia Yen Liew, Veeranjaneyulu Gannedi, Shang-Cheng Hung, and Chi-Kung Ni, “Unusual free oligosaccharides in human bovine and caprine milk,” Scientific Reports, 2022, 12, 10790.

2.        Hock-Seng Nguan, Shang-Ting Tsai, and Chi-Kung Ni, “Collision-Induced Dissociation of Cellobiose and Maltose,” J. Phys. Chem. A, 2022, 126, 9, 1486–1495

3.        Shang-Ting Tsai, and Chi-Kung Ni. “Differentiation of aldohexoses and ketohexoses through collision-induced dissociation,” J. Chin. Chem. Soc., 2021, (published on line on 23 Sep, http://doi.org/10.1002/jccs.202100257).

4.        Chia Yen Liew, Chieh-Kai Chan, Shih-Pei Huang, Yu-Ting Cheng, Shang-Ting Tsai, Hsu Chen Hsu, Cheng-Chung Wang, and Chi-Kung Ni. “De novo structural determination of oligosaccharide isomers in glycosphingolipids using logically derived sequence tandem mass spectrometry,” Analyst, 2021, 146, 7345-7357.

5.        Shang-Ting Tsai, Hock-Seng Nguan, and Chi-Kung Ni. “Identification of anomericity and linkage of arabinose and ribose through collision induced dissociation,” J. Phys. Chem. A, 2021, 125(28), 6109-6121.

6.        Chia Yen Liew, Chu-Chun Yen, Jien-Lian Chen, Shang-Ting Tsai, Sujeet Pawar, Chung-Yi Wu, and Chi-Kung Ni. “Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry,” Commun. Chem. 2021, 4, 92.

7.        Shih-Pei Huang, Hsu Chen Hsu, Chia Yen Liew, Shang-Ting Tsai, and Chi-Kung Ni, “Logically derived sequence tandem mass spectrometry for structural determination of galactose oligosaccharides,” Glycoconj J, 2021, 38, 177-189.

8.        Chi-Kung Ni, Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, and Shang-Ting Tsai. “Modern Mass Spectrometry Techniques for Oligosaccharide Structure Determination: Logically derived sequence tandem mass spectrometry for automatic oligosaccharide structural determination,” Comprehensive Glycoscience, 2^nd edition, edited by Joseph J. Barchi, Jr., Elsevier, Oxford, 2021.

9.        Chun-Yuan Cheng, Lassina Barro, Shang-Ting Tsai, Tai-Wei Feng, Xiao-Yu Wu, Che-Wei Chao, Ruei-Siang Yu, Ting-Yu Chin, and Ming Fa Hsieh, "Epigallocatechin-3-Gallate-Loaded Liposomes Favor Anti-Inflammation of Microglia Cells and Promote Neuroprotection," Int. J. Mol. Sci. 2021, 22(6), 3037.

10.     Hock-Seng Nguan*, Shang-Ting Tsai*(*Equal contributions), Jien-Liang Chen, Po-Jen Hsu, Jer-Lai Kuo and Chi-Kung Ni, “Collision-induced dissociation of xylose and its applications in linkage and anomericity identification,” Phys. Chem. Chem. Phys, 2021, 23 (5), 3485-3495.

11.     Chi-Kung Ni, Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, and Shang-Ting Tsai, “Modern Mass Spectrometry Techniques for Oligosaccharide Structure Determination: Logically Derived Sequence Tandem Mass Spectrometry for Automatic Oligosaccharide Structural Determination,” Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020, DOI: 10.1016/B978-0-12-409547-2.14903-0.

12.     Imran Ali , Mosa H. Alsehli, Luciana Scotti, Marcus Tullius Scotti, Shang-Ting Tsai, Ruei-Siang Yu, Ming Fa Hsieh, and Jung-Chih Chen, “Progress in Polymeric Nano-Medicines for Theranostic Cancer Treatment,” Polymers, 2020, 16(3), 598.

13.     Shang-Ting Tsai, Chia Yen Liew, Hsu Chen Hsu, Shih-Pei Huang, Wei-Chien Weng, Yu-Hsiang Kuo, and Chi-Kung Ni, “Automatically Full Glycan Structural Determination with Logically Derived Sequence Tandem Mass Spectrometry,” ChemBioChem., 2019, 16, 2351-2359.

14.     Cheng-chau Chiu, Hai Thi Huynh, Shang-Ting Tsai, Hou-Yu Lin, Po-Jen Hsu, Huu Trong Phan, Arya Karumanthra, Hayden Thompson, Yu-Chi Lee, Jer-Lai Kuo, and Chi-Kung Ni, “Toward Closing the Gap between Hexoses and N‑Acetlyhexosamines: Experimental and Computational Studies on the Collision-Induced Dissociation of Hexosamines,” J. Phys. Chem. A, 2019, 123(31), 6683−6700.

15.     Hsu Chen Hsu, Shih-Pei Huang, Chia Yen Liew, Shang-Ting Tsai and Chi-Kung Ni, “De Novo Structural Determination of Mannose Oligosaccharides by Using a Logically Derived Sequence for Tandem Mass Spectrometry,” Anal. Bioanal. Chem. 2019, 411(15), 3241-3255.

16.     Cheng-Chau Chiu, Shang-Ting Tsai, Po-Jen Hsu, HaiThi Huynh, Jien-Lian Chen, Huu Trong Phan, Shih-Pei Huang, Hou-Yu Lin, Jer-Lai Kuo, and Chi-Kung Ni, “Unexpected Dissociation Mechanism of Sodiated N-Acetylglucosamine and N-Acetylgalactosamine,” J. Phys. Chem. A, 2019, 123 (16), 3441–3453.

17.     Yu-Hsuan Shen, Shang-Ting Tsai, Chia Yen Liew, and Chi-Kung Ni, “Mass spectrometry-based identification of carbohydrate anomeric configuration to determine the mechanism of glycoside hydrolases,” Carbohydr. Res., 2019, 476(1), 53-59.

18.     Hai Thi Huynh, Huu Trong Phan, Po-Jen Hsu, Jien-Lian Chen, Hock Seng Nguan, Shang-Ting Tsai, Thantip Roongcharoen, Chia Yen Liew, Chi-Kung Ni, and Jer-Lai Kuo, “Collision-induced dissociation of sodiated glucose, galactose, and mannose, and the identification of anomeric configuration,” Phys. Chem. Chem. Phys.,2018, 20(29), 19614-19624.

19.     Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, Shang-Ting Tsai, and Chi-Kung Ni, “Simple Method for De Novo Structural Determination of Underivatised Glucose Oligosaccharides,” Scientific Reports, 2018, 8(1), 5562.

20.     Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, Shang-Ting Tsai, and Chi-Kung Ni, “Simple Approach for De Novo Structural Identification of Mannose Trisaccharides,” J. Am. Soc. Mass Spectrom., 2018, 29(3), 470-480.

21.     Shang-Ting Tsai, Jien-Lian Chen, and Chi-Kung Ni, “Does low-energy collision-induced dissociation of lithiated and sodiated carbohydrates always occur at anomeric carbon of the reducing end?,” Rapid Commun. Mass Spectrom., 2017, 31(21), 1835-1844.

22.     Sheng-Ping Liang, I-Chung Lu, Shang-Ting Tsai, Jien-Lian Chen, Yuan Tseh Lee, and Chi-Kung Ni, “Laser Pulse Width Dependence and Ionization Mechanism of Matrix-Assisted Laser Desorption/Ionization,” J. Am. Soc. Mass Spectrom., 2017, 28(10), 2235-2245.

23.     Jien-Lian Chen, Hock Seng Nguan, Po-Jen Hsu, Shang-Ting Tsai, Chia Yen Liew, Jer-Lai Kuo, Wei-Ping Hu, and Chi-Kung Ni, “Collision-induced dissociation of sodiated glucose and identification of anomeric configuration,” Phys. Chem. Chem. Phys., 2017, 19(23), 15454-15462.

24.     Yuri A. Dyakov, Shang-Ting Tsai, Arnab Bagchi, Chien-Ming Tseng, Yuan Tseh Lee and Chi-Kung Ni, “355 nm multiphoton dissociation and ionization of 2, 5-dihydroxyacetophenone,” J. Phys. Chem. A., 2009, 113(52), 14987-14994.

25.     Shang-Ting Tsai, Chung-Hsuan Chen, Yuan Tseh Lee, and Yi-Sheng Wang, “Desorption Dynamics of Neutral Molecules in Matrix-assisted Laser Desorption/Ionization,” Mol. Phys., 2008, 106(2-4), 239-247.

26.     Ming-Hsin Li, Shang-Ting Tsai, Chung-Hsuan Chen, Chiu Wen Chen, Yuan Tseh Lee, and Yi-Sheng Wang, “Bipolar Ion Detector Based on Sequential Conversion Reactions,” Anal. Chem., 2007, 79(4), 1277-1282.

27.     Shang-Ting Tsai, Chiu Wen Chen, Ling Chu Lora Huang, Min-Chia Huang, Chung-Hsuan Chen, and Yi-Sheng Wang, “Simultaneous mass analysis of positive and negative ions using a dual-polarity time-of-flight mass spectrometer,” Anal. Chem., 2006, 78(22), 7729-7734.

28.     Shang-Ting Tsai, Jyh-Chiang Jiang, Ming-Fu Lin, Yuan Tseh Lee, and Chi-Kung Ni, “Carbon–carbon bond cleavage in the photoionization of ethanol and 1-propanol clusters,” J. Chem. Phys., 2004, 120(19), 8979-8984.

29.     Shang-Ting Tsai, Cheng-Liang Huang, Yuan T. Lee, and Chi-Kung Ni, “Ring opening dissociation of d6-benzene,” J. Chem. Phys., 2001, 115(6), 2449-2455.

30.     Shang-Ting Tsai, Chih-Kai Lin, Yuan T. Lee, and Chi-Kung Ni, “Multimass Ion Imaging Detection: Application to Photodissociation,” Rev. Sci. Instrum., 2001, 72(4), 1963-1969.

31.     Shang-Ting Tsai, Chih-Kai Lin, Yuan T. Lee, and Chi-Kung Ni, “Dissociation rate of hot benzene,” J. Chem. Phys., 2000, 113(1), 67-70.

32.     Shang-Ting Tsai, Yuan T. Lee, and Chi-Kung Ni, “Photodissociation of Benzotrifluoride at 193 nm,” J. Phys. Chem. A., 2000, 104(45), 10125-10130.

33.     Shang-Ting Tsai, Jyh-Chiang Jiang, Yuan T. Lee, A. H. Kung, Sheng Hsien Lin, and Chi-Kung Ni, “Photoionization of methanol dimer using a tunable vacuum ultraviolet laser,” J. Chem. Phys., 1999, 111(8), 3434-3440.