蔡尚庭
一、學歷：
台灣大學物理研究所博士 (2000)
台灣大學物理研究所碩士 (1996)
台灣大學化學系學士 (1993)
二、經歷：
三、專業領域：
醣體學、分析化學、物理化學、儀器設計與製造
四、連絡方式（ Tel or e-mail)：
Tel:05-2717920
e-mail:sttsai@mail.ncyu.edu.tw
五、研究方向：
醣類分子質譜鑑定方法與相關儀器開發
醣類分子分解機制研究
有機分子萃取與分離方法與相關儀器開發
六、期刊著作：
Paper
1. Wei-Chien Weng, Hung-En Liao, Shih-Pei Huang, Shang-Ting Tsai, Hsu-Chen Hsu, Chia Yen Liew, Veeranjaneyulu Gannedi, Shang-Cheng Hung, and Chi-Kung Ni, “Unusual free oligosaccharides in human bovine and caprine milk,” Scientific Reports, 2022, 12, 10790.
2. Hock-Seng Nguan, Shang-Ting Tsai, and Chi-Kung Ni, “Collision-Induced Dissociation of Cellobiose and Maltose,” J. Phys. Chem. A, 2022, 126, 9, 1486–1495
3. Shang-Ting Tsai, and Chi-Kung Ni. “Differentiation of aldohexoses and ketohexoses through collision-induced dissociation,” J. Chin. Chem. Soc., 2021, (published on line on 23 Sep, http://doi.org/10.1002/jccs.202100257).
4. Chia Yen Liew, Chieh-Kai Chan, Shih-Pei Huang, Yu-Ting Cheng, Shang-Ting Tsai, Hsu Chen Hsu, Cheng-Chung Wang, and Chi-Kung Ni. “De novo structural determination of oligosaccharide isomers in glycosphingolipids using logically derived sequence tandem mass spectrometry,” Analyst, 2021, 146, 7345-7357.
5. Shang-Ting Tsai, Hock-Seng Nguan, and Chi-Kung Ni. “Identification of anomericity and linkage of arabinose and ribose through collision induced dissociation,” J. Phys. Chem. A, 2021, 125(28), 6109-6121.
6. Chia Yen Liew, Chu-Chun Yen, Jien-Lian Chen, Shang-Ting Tsai, Sujeet Pawar, Chung-Yi Wu, and Chi-Kung Ni. “Structural identification of N-glycan isomers using logically derived sequence tandem mass spectrometry,” Commun. Chem. 2021, 4, 92.
7. Shih-Pei Huang, Hsu Chen Hsu, Chia Yen Liew, Shang-Ting Tsai, and Chi-Kung Ni, “Logically derived sequence tandem mass spectrometry for structural determination of galactose oligosaccharides,” Glycoconj J, 2021, 38, 177-189.
8. Chi-Kung Ni, Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, and Shang-Ting Tsai. “Modern Mass Spectrometry Techniques for Oligosaccharide Structure Determination: Logically derived sequence tandem mass spectrometry for automatic oligosaccharide structural determination,” Comprehensive Glycoscience, 2nd edition, edited by Joseph J. Barchi, Jr., Elsevier, Oxford, 2021.
9. Chun-Yuan Cheng, Lassina Barro, Shang-Ting Tsai, Tai-Wei Feng, Xiao-Yu Wu, Che-Wei Chao, Ruei-Siang Yu, Ting-Yu Chin, and Ming Fa Hsieh, "Epigallocatechin-3-Gallate-Loaded Liposomes Favor Anti-Inflammation of Microglia Cells and Promote Neuroprotection," Int. J. Mol. Sci. 2021, 22(6), 3037.
10. Hock-Seng Nguan*, Shang-Ting Tsai*(*Equal contributions), Jien-Liang Chen, Po-Jen Hsu, Jer-Lai Kuo and Chi-Kung Ni, “Collision-induced dissociation of xylose and its applications in linkage and anomericity identification,” Phys. Chem. Chem. Phys, 2021, 23 (5), 3485-3495.
11. Chi-Kung Ni, Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, and Shang-Ting Tsai, “Modern Mass Spectrometry Techniques for Oligosaccharide Structure Determination: Logically Derived Sequence Tandem Mass Spectrometry for Automatic Oligosaccharide Structural Determination,” Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020, DOI: 10.1016/B978-0-12-409547-2.14903-0.
12. Imran Ali , Mosa H. Alsehli, Luciana Scotti, Marcus Tullius Scotti, Shang-Ting Tsai, Ruei-Siang Yu, Ming Fa Hsieh, and Jung-Chih Chen, “Progress in Polymeric Nano-Medicines for Theranostic Cancer Treatment,” Polymers, 2020, 16(3), 598.
13. Shang-Ting Tsai, Chia Yen Liew, Hsu Chen Hsu, Shih-Pei Huang, Wei-Chien Weng, Yu-Hsiang Kuo, and Chi-Kung Ni, “Automatically Full Glycan Structural Determination with Logically Derived Sequence Tandem Mass Spectrometry,” ChemBioChem., 2019, 16, 2351-2359.
14. Cheng-chau Chiu, Hai Thi Huynh, Shang-Ting Tsai, Hou-Yu Lin, Po-Jen Hsu, Huu Trong Phan, Arya Karumanthra, Hayden Thompson, Yu-Chi Lee, Jer-Lai Kuo, and Chi-Kung Ni, “Toward Closing the Gap between Hexoses and N‑Acetlyhexosamines: Experimental and Computational Studies on the Collision-Induced Dissociation of Hexosamines,” J. Phys. Chem. A, 2019, 123(31), 6683−6700.
15. Hsu Chen Hsu, Shih-Pei Huang, Chia Yen Liew, Shang-Ting Tsai and Chi-Kung Ni, “De Novo Structural Determination of Mannose Oligosaccharides by Using a Logically Derived Sequence for Tandem Mass Spectrometry,” Anal. Bioanal. Chem. 2019, 411(15), 3241-3255.
16. Cheng-Chau Chiu, Shang-Ting Tsai, Po-Jen Hsu, HaiThi Huynh, Jien-Lian Chen, Huu Trong Phan, Shih-Pei Huang, Hou-Yu Lin, Jer-Lai Kuo, and Chi-Kung Ni, “Unexpected Dissociation Mechanism of Sodiated N-Acetylglucosamine and N-Acetylgalactosamine,” J. Phys. Chem. A, 2019, 123 (16), 3441–3453.
17. Yu-Hsuan Shen, Shang-Ting Tsai, Chia Yen Liew, and Chi-Kung Ni, “Mass spectrometry-based identification of carbohydrate anomeric configuration to determine the mechanism of glycoside hydrolases,” Carbohydr. Res., 2019, 476(1), 53-59.
18. Hai Thi Huynh, Huu Trong Phan, Po-Jen Hsu, Jien-Lian Chen, Hock Seng Nguan, Shang-Ting Tsai, Thantip Roongcharoen, Chia Yen Liew, Chi-Kung Ni, and Jer-Lai Kuo, “Collision-induced dissociation of sodiated glucose, galactose, and mannose, and the identification of anomeric configuration,” Phys. Chem. Chem. Phys.,2018, 20(29), 19614-19624.
19. Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, Shang-Ting Tsai, and Chi-Kung Ni, “Simple Method for De Novo Structural Determination of Underivatised Glucose Oligosaccharides,” Scientific Reports, 2018, 8(1), 5562.
20. Hsu Chen Hsu, Chia Yen Liew, Shih-Pei Huang, Shang-Ting Tsai, and Chi-Kung Ni, “Simple Approach for De Novo Structural Identification of Mannose Trisaccharides,” J. Am. Soc. Mass Spectrom., 2018, 29(3), 470-480.
21. Shang-Ting Tsai, Jien-Lian Chen, and Chi-Kung Ni, “Does low-energy collision-induced dissociation of lithiated and sodiated carbohydrates always occur at anomeric carbon of the reducing end?,” Rapid Commun. Mass Spectrom., 2017, 31(21), 1835-1844.
22. Sheng-Ping Liang, I-Chung Lu, Shang-Ting Tsai, Jien-Lian Chen, Yuan Tseh Lee, and Chi-Kung Ni, “Laser Pulse Width Dependence and Ionization Mechanism of Matrix-Assisted Laser Desorption/Ionization,” J. Am. Soc. Mass Spectrom., 2017, 28(10), 2235-2245.
23. Jien-Lian Chen, Hock Seng Nguan, Po-Jen Hsu, Shang-Ting Tsai, Chia Yen Liew, Jer-Lai Kuo, Wei-Ping Hu, and Chi-Kung Ni, “Collision-induced dissociation of sodiated glucose and identification of anomeric configuration,” Phys. Chem. Chem. Phys., 2017, 19(23), 15454-15462.
24. Yuri A. Dyakov, Shang-Ting Tsai, Arnab Bagchi, Chien-Ming Tseng, Yuan Tseh Lee and Chi-Kung Ni, “355 nm multiphoton dissociation and ionization of 2, 5-dihydroxyacetophenone,” J. Phys. Chem. A., 2009, 113(52), 14987-14994.
25. Shang-Ting Tsai, Chung-Hsuan Chen, Yuan Tseh Lee, and Yi-Sheng Wang, “Desorption Dynamics of Neutral Molecules in Matrix-assisted Laser Desorption/Ionization,” Mol. Phys., 2008, 106(2-4), 239-247.
26. Ming-Hsin Li, Shang-Ting Tsai, Chung-Hsuan Chen, Chiu Wen Chen, Yuan Tseh Lee, and Yi-Sheng Wang, “Bipolar Ion Detector Based on Sequential Conversion Reactions,” Anal. Chem., 2007, 79(4), 1277-1282.
27. Shang-Ting Tsai, Chiu Wen Chen, Ling Chu Lora Huang, Min-Chia Huang, Chung-Hsuan Chen, and Yi-Sheng Wang, “Simultaneous mass analysis of positive and negative ions using a dual-polarity time-of-flight mass spectrometer,” Anal. Chem., 2006, 78(22), 7729-7734.
28. Shang-Ting Tsai, Jyh-Chiang Jiang, Ming-Fu Lin, Yuan Tseh Lee, and Chi-Kung Ni, “Carbon–carbon bond cleavage in the photoionization of ethanol and 1-propanol clusters,” J. Chem. Phys., 2004, 120(19), 8979-8984.
29. Shang-Ting Tsai, Cheng-Liang Huang, Yuan T. Lee, and Chi-Kung Ni, “Ring opening dissociation of d6-benzene,” J. Chem. Phys., 2001, 115(6), 2449-2455.
30. Shang-Ting Tsai, Chih-Kai Lin, Yuan T. Lee, and Chi-Kung Ni, “Multimass Ion Imaging Detection: Application to Photodissociation,” Rev. Sci. Instrum., 2001, 72(4), 1963-1969.
31. Shang-Ting Tsai, Chih-Kai Lin, Yuan T. Lee, and Chi-Kung Ni, “Dissociation rate of hot benzene,” J. Chem. Phys., 2000, 113(1), 67-70.
32. Shang-Ting Tsai, Yuan T. Lee, and Chi-Kung Ni, “Photodissociation of Benzotrifluoride at 193 nm,” J. Phys. Chem. A., 2000, 104(45), 10125-10130.
33. Shang-Ting Tsai, Jyh-Chiang Jiang, Yuan T. Lee, A. H. Kung, Sheng Hsien Lin, and Chi-Kung Ni, “Photoionization of methanol dimer using a tunable vacuum ultraviolet laser,” J. Chem. Phys., 1999, 111(8), 3434-3440.
Patent
34. Chi-Kung Ni, Shang-Ting Tsai, Hsu Chen Hsu, Chia Yen Liew and Shih-Pei Huang, “Structural determination of carbohydrates using special procedure and database of mass spectra,” US Patent 10,796,788, filed June 18 2018 and issued Oct 6 2020.
35. 謝明發，沈博元，蔡尚庭，多微孔骨支架之製造方法 (Method for Manufacturing Multi-microporous Bone Scaffold)，2020年2月12日智財局提出發明專利申請，申請號109104397。
36. 謝明發，蔡尚庭，林子超，李文婷，葛宗融，卓世川，螢光成像方法與系統(Fluorescence Imaging Method and System)，2020年1月21日智財局提出發明專利申請，申請號109102228。2021年1月15日申請美國專利，申請案號為17/150,488。
37. 謝義禾，謝明發，蔡尚庭，生物可吸收可注射骨複合材料及其注射方法 (Biodegradable injectable bone composite and its injection method thereof)，2019年10月9日向智財局提出發明專利申請，申請號108136681。
38. Yi-Sheng Wang, Shang-Ting Tsai, “Particle detector,” US Patent 7,714,299, filed August 8 2006 and issued May 11 2010.
39. Yi-Sheng Wang, Chung-Hsuan Chen, Shang-Ting Tsai, Chiu Wen Chen, “Dual-polarity mass spectrometer,” US Patent 7,649,170, filed October 3 2006 and issued January 19 2010.
40. Chung-Long Chang, Jui-Cheng Lo, Shang-Ting Tsai, Yu-Liang Lin, “Method to solve alignment mark blinded issues and technology for application of semiconductor etching at a tiny area,” US Patent 7,125,521, filed April 26 2004 and issued October 24 2006.
41. Shang-Ting Tsai, Ping Chuang, Henry Lo, Chao-Jung Chang, Ping-Hsu Chen, Yu-Liang Lin, Yu-Huei Chen, Ai-Sen Liu, Syun-Ming Jang, “Method and system for in-situ monitoring of mixing ratio of high selectivity slurry,” US Patent 6,884,149, filed April 27 2004 and issued April 26 2005.
七、 研討會論文
1. 第十六屆台灣質譜學會年會 口頭報告標題 “Automatic Identification of Glycan Full Structure with Logically Derived Sequence (LODES) Tandem Mass Spectrometry,” Shang-Ting Tsai, July 3-5, 2019
2. 2019 Canadian Glycomics Symposium, Selected Talk Title: “Automatic identification of full structure of glycan with logically derived sequence tandem mass spectrometry,” Shang-Ting Tsai, May 15-17, 2019, Banff, Canada.
3. 2019 Canadian Glycomics Symposium, Poster Title: “Automatic identification of full structure of glycan with logically derived sequence tandem mass spectrometry,” Shang-Ting Tsai, May 15-17, 2019, Banff, Canada.
4. 第十五屆台灣質譜學會年會 壁報論文標題 “Identification of Constituent Monosaccharides, Anomeric Configurations, and Linkages of Oligosaccharides,” Shang-Ting Tsai, July 18-20, 2018.
5. 65th ASMS Conference, Poster ID number: 289308, “Does low energy CID always occur on the reducing end of carbohydrate?” Shang-Ting Tsai, June 4-8, 2017 Indianapolis, Indiana.
八、研究計畫：
九、其他：
十、教授課目：